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Comparative Effects of Smoking Marihuana or Placebo on Human Motor and Mental Performance

Key Findings: A double blind study of subjects smoking both a marijuana cigarette and a placebo showed a significant decrement of motor and mental performance associated with marijuana. The study was designed to quantitate “pharmacological” effects on performance and deliberately avoided the intensely subjective phenomenon of the “high”.


Authors: Joseph E. Manno M.S. Glenn F. Kiplinger M.D., Ph.D. Susan E. Haine Ivan F. Bennett M.D. Robert B. Forney Ph.D.


View abstract on American Society for Clinical Pharmacology & Therapeutics (ASCPT)